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When melanocytes are hyperactivated by specific triggers UV radiation, post-inflammatory signals from acne or injury, hormonal changes (especially estrogen and progesterone in melasma), or genetic predisposition they produce excess melanin that accumulates in patches, creating dark spots, uneven tone and visible discolouration

Reduced glutathione 1000mg does not benefit much because it is not readily absorbed and has not undergone this process

Pinch the skin at the injection site to create a fold of subcutaneous tissue

Leaders should proactively model: Gross margin sensitivity Program pricing flexibility Inventory risk exposure Cash flow implications 5